Announcements

News about Syantra and its revolutionary approach to cancer screening.

Real-world stories from women impacted by breast cancer

We’re honored to share stories of some people directly impacted by breast cancer. It’s stories like these — it’s people like this — that inspire us in our mission to make early cancer detection part of routine healthcare.

Diagnostic platform publications

Breast Cancer Whole Blood Screening: Analytical and Clinical Performance from Early Analysis of the International Identify Breast Cancer (IDBC) Study

European Journal of Cancer 175, Suppl. 1 (2022) S1–S96

[Poster] Breast Cancer Whole Blood Screening: Analytical and Clinical Performance from Early Analysis of the International Identify Breast Cancer (IDBC) Study

A poster illustrating analytical and clinical performance of the Syantra DX™ Breast Cancer test for detecting an active breast cancer signature from early analysis of the international identify breast cancer (IDBC) study. Presented at the The 13th European Breast Cancer Conference in November 2022.

A whole blood assay to identify breast cancer: interim analysis of the international identify breast cancer (IDBC) study evidence supporting the Syantra DX Breast Cancer test.

San Antonio Breast Cancer Symposium Meeting Abstracts page 667; presentation Dec. 8, 2021, USA

[Poster] A whole blood assay to identify breast cancer: interim analysis of the International Identify Breast Cancer (IDBC) study evidence supporting the Syantra DX Breast Cancer test

A poster illustrating an interim analysis of the international identify breast cancer (IDBC) study evidence supporting the Syantra DX | Breast Cancer test. Presented at the San Antonio Breast Cancer Symposium in December 2021.

Fluid Flow Stimulation Modulates Expression of S100 Genes in Normal Breast Epithelium and Breast Cancer

Cellular and Molecular Bioengineering (2021)

Fluid flow exposure promotes epithelial-to-mesenchymal transition and adhesion of breast cancer cells to endothelial cells

Breast Cancer Research (2021)

Linking Aortic Mechanical Properties, Gene Expression and Microstructure: A New Perspective on Regional Weakening in Abdominal Aortic Aneurysms

Frontiers in Cardiovascular Medicine (2021) 8, 1-14

Quantitative RT-PCR assay of HER2 mRNA expression in formalin-fixed and paraffin-embedded breast cancer tissues

Int J Clin Exp Pathol. (2014) 7, 6752–6759

Evaluation of a quantitative RT-PCR assay to detect HER2 mRNA overexpression for diagnosis and selection of trastuzumab therapy in breast cancer tissue samples

Exp. Mol. Pathol. (2014) 97, 368–374

Discovery platform publications

Apabetalone (RVX-208) reduces vascular inflammation in vitro and in CVD patients by a BET-dependent epigenetic mechanism

Clinical Epigenetics (2019) 11: 102, 1-21

17-DMAG regulates p21 expression to induce chondrogenesis in vitro and in vivo

Disease Models & Mechanisms (2018) 11(10). pii: dmm033662

Viral manipulation of a novel mechanoresponsive signaling axis disassembles processing bodies

BioRxIV, under review

A human cell model for dynamic testing of MR contrast agents

Biotechniques, 50:120-123

Long term shear stress leads to increased phosphorylation of multiple MAPK species in cultured human aortic endothelial cells

Biorheology (2009) 46(6): 529-538

Flow-dependent Smad2 phosphorylation and TGIF nuclear localization in human aortic endothelial cells

Am J Physiol Heart Circ Physiol (2011) 301(1): H98–H107.doi: 10.1152/ajpheart.00668.2010

Methicillin resistant Staphylococcus aureus adhesion to human umbilical vein endothelial cells demonstrates wall shear stress dependent behaviour

BioMedical Engineering OnLine (2011) Mar 22;10:20

Fluid Flow Modulation of Murine Embryonic Stem Cell Pluripotency Gene Expression in the Absence of LIF

Cellular and Molecular Bioengineering (2013) 6: 335-345